Zinc Layered Hydroxide-Sodium Dodecyl Sulphate-Isoprocarb Modified Multiwalled Carbon Nanotubes as sensor for Electrochemical Determination of Dopamine in Alkaline Medium

A sensitive and selective electrochemical sensor for detection of dopamine (DOP) using zinc layered
hydroxide-sodium dodecyl sulphate-isoprocarb (ZLH-SDS-I)/multiwalled carbon nanotubes
(MWCNT) in 100 mM phosphate buffer solution (PBS) and at the pH 8.0 was developed. The
morphology and electrochemistry properties of ZLH-SDS-I/MWCNT nanocomposites were
characterized using square wave voltammetry (SWV), transmission electron microscopy (TEM), cyclic
voltammetry (CV), electrochemical impedence spectroscopy (EIS) and scanning electron microscopy
(SEM). Under optimized conditions, the linear analytical curve for determination of dopamine was 1.0
µM to 0.3 mM with the detection limit of 0.43 µM. Besides that, the proposed sensor also exhibited
good selectivity, stability, sensitivity and was found to be applicable for dopamine detection in the
commercial dopamine hydrochloride injection samples.