Perbedaan Kadar Tumor Necrosis Factor - Alfa Antara Diabetes Mellitus Tipe 2 Terkontrol dengan Tidak Terkontrol

Yuniarti, Elsa (2017) Perbedaan Kadar Tumor Necrosis Factor - Alfa Antara Diabetes Mellitus Tipe 2 Terkontrol dengan Tidak Terkontrol. Bioeducation Journal, 1 (1). pp. 18-29. ISSN Print: 2354-8363 online: ISSN 2615-5451

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Abstract

Hyperglicemia in DM Type will induce macrofag to produce cytokin proinflamation TNF-α. High levels of TNF-α in DM Type 2 can lead to more severe insulin resistance and become involved in endothelial dysfunction which lead to complications of the disease. This research aims to know differences between TNF-α level in DM type 2 controlled and uncontrolled. This research used obervational analizing method and cross sectional study comparative approach. Blood samples are grouped to 35 patient DM type 2 controlled and uncontrolled in the medicinal treatment in Padang State University polyclinic. The level of serum TNF-α will be examined in Biomedical Laboratory FKUA using ELISA method. TNF-α level in the diabetes type 2 controlled on average 7,55 ± 0,43 pg/ml whereas uncontrolled on average 149,28 ± 26,82 pg/ml. The Mann-Whitney test showed a p value < 0,001. There are significant differences in the levels of TNF-α in patients with DM type 2 controlled and uncontrolled.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Biologi - S1
Depositing User: Mrs. Wiwi Sartika
Date Deposited: 30 Apr 2019 01:11
Last Modified: 30 Apr 2019 01:11
URI: http://repository.unp.ac.id/id/eprint/21916

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